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In vitro biocompatibility of titanium-nickel alloy with titanium oxide film by H2O2 oxidation

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【作者】 胡涛储成林尹立红浦跃朴董寅生郭超盛晓波钟志源朱剑豪

【Author】 HU Tao1, CHU Cheng-lin1, YIN Li-hong2, PU Yao-pu2, DONG Yin-sheng1, GUO Chao1, SHENG Xiao-bo1, CHUNG Jonat han-CY3, CHU Paul-K3 1. School of Materials Science and Engineering, Southeast University, Nanjing 211189, China; 2. School of Public Health, Southeast University, Nanjing 210096, China; 3. Department of Physics and Materials Science, City University of Hong Kong, Hong Kong, China

【机构】 School of Materials Science and Engineering Southeast UniversitySchool of Materials Science and Engineering Southeast UniversitySchool of Public Health Southeast UniversityDepartment of Physics and Materials Science City University of Hong KongNanjing 211189 ChinaNanjing 210096 ChinaHong Kong China

【摘要】 Titanium oxide film with a graded interface to NiTi matrix was synthesized in situ on NiTi shape memory alloy(SMA) by oxidation in H2O2 solution. In vitro studies including contact angle measurement, hemolysis, MTT cytotoxicity and cell morphology tests were employed to investigate the biocompatibility of the H2O2-oxidized NiTi SMAs with this titanium oxide film. The results reveal that wettability, blood compatibility and fibroblasts compatibility of NiTi SMA are improved by the coating of titanium oxide film through H2O2 oxidation treatment.

【Abstract】 Titanium oxide film with a graded interface to NiTi matrix was synthesized in situ on NiTi shape memory alloy(SMA) by oxidation in H2O2 solution. In vitro studies including contact angle measurement, hemolysis, MTT cytotoxicity and cell morphology tests were employed to investigate the biocompatibility of the H2O2-oxidized NiTi SMAs with this titanium oxide film. The results reveal that wettability, blood compatibility and fibroblasts compatibility of NiTi SMA are improved by the coating of titanium oxide film through H2O2 oxidation treatment.

【基金】 Project(50501007) supported by the National Natural Science Foundation of China;Project supported by Program for New Century Excellent Talents(NCET) in University of Ministry of Education of China;Project(7001999) supported by the SRG grant from the Research Committee of the CityU of HK;Project(4012001007) supported by the Teaching and Research Award Program for Outstanding Young Teachers of Southeast University, China
  • 【文献出处】 Transactions of Nonferrous Metals Society of China ,中国有色金属学会会刊(英文版) , 编辑部邮箱 ,2007年03期
  • 【分类号】TG174.45
  • 【被引频次】14
  • 【下载频次】63
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