【摘要】 目的探讨广西桂西地区壮族癫痫患者的生活质量(QOL)及其影响因素。方法采用癫痫患者生活质量量表-31(QOLIE-31)对78例临床确诊的癫痫患者和60名正常对照者进行评定,并分析不同因素对患者QOL的影响。结果癫痫组的QOLIE-31评分(53.9±8.0)较对照组(77.0±7.1)显著降低(P<0.01)。不同性别、用药数量、病程及发作类型的患者QOLIE-31评分相比较,性别方面差异无显著性(P>0.05),单药较多药治疗者评分高(P<0.01),病程短较病程长者评分高(P<0.05),强直-阵挛发作较其他发作类型者评分低(P<0.01)。结论广西桂西地区壮族癫痫患者QOL明显低于同地区正常人群,用药和发作类型对患者的QOL影响较大。更多还原

【Abstract】 Objective To investigate the quality of life (QOL) and its influence factors in epilepsy patients in Zhuang population in Guangxi Guixi area. Methods Totally 78 epilepsy patients in Zhuang populations and 60 healthy controls were enrolled, and their QOL was assessed with Quality of Life in Epilepsy Inventory-31 (QOLIE-31). The QOLIE-31 scores of patients between different sexes, anti-epileptic drugs (AEDs) usage, duration of seizure, and seizure types were compared. Results QOL score was significantly lower in epileptic group (53.9±8.0) compared with control group (77.0±7.1) (P<0.01). No difference was found in QOLIE-31 scores of patients between men and women (P>0.05). Patients with single AED, shorter duration of seizure, and tonic-clonic seizure had higher QOLIE-31 scores than those with multiple AEDs, longer duration of seizure, and other seizure types (P<0.01, P<0.05, P<0.01, respectively). Conclusions QOL is lower in epilepsy patients than normal people in Zhuang populations in Guangxi Guixi area. Medication and seizure type affects the QOL in patients with epilepsy.更多还原