【摘要】 目的:了解重型肝炎患者甲种胎儿球蛋白(AFP)的变化。方法:38例重型肝炎患者,根据临床转归分为存活组和死亡组。入院后动态观察AFP的改变。用放免法检测血清AFP。结果:38例重型肝炎患者的AFP(205.64±289.78)ng/m l,显著高于正常值(8.1ng/m l),P<0.001。存活组22例患者的AFP(225.03±65.16)ng/m l,显著高于正常值,P=0.003。但是,两组间的AFP差异无显著性意义(P=0.63)。38例重型肝炎中,6例患者的AFP在700~900ng/m l之间,10例在100~500ng/m l之间,其余均高于正常值的2~10倍(尤以存活组较为明显),仅4例在正常值范围之内。结论:重型肝炎有强烈的肝细胞再生现象,肝细胞再生能力对患者的预后有一定影响。更多还原

【Abstract】 Objective:To investigate the changes of alpha fetoprotein(AFP) in patients with severe hepatitis.Methods:Thirty eight patients were divided into two groups-the survival(22 cases) and the dead(16 cases) by clinical inversion.AFP levels were measured with radioimmunoassay(RIA) to observe the changes of AFP in the patients hospitalized.Results:AFP(205.64±289.67)ng/ml in the severe patients was obviously higher than that of the normal(8.1ng/ml),P<0.001.There were no significant difference between the former[AFP(225.03±65.16)ng/ml] and latter[AFP(178.97±68.48)ng/ml,P=0.63].AFP of 6 patients were in 700～900ng/ml and 10 in 100～500ng/ml.The others were from twice to 10 times higher than that of the normal and only 4 in normal.Conclusions:It was showed there was a hepatocellular regeneration strongly appeared in severe heaptitis.更多还原