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咳咳止口服液质控方法的研究

Quality control of Kekezhi Koufuye

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【作者】 曹冬红; 苏辉; 邓泽宜;

【Author】 CAO Dong-hong,SU Hui,DENG Ze-yi(Fourth People’s Hospital of Changde,Changde Hunan 415000;Third People’s Hospital of Changde,Changde Hunan 415000;Linli People’s Hospital of Hunan Province,Linli Hunan 415200)

【机构】 常德市第四人民医院; 常德市第三人民医院; 湖南临澧县人民医院 湖南常德415000; 湖南常德415000; 湖南常德415200;

【摘要】 目的建立咳咳止口服液的质量标准。方法采用薄层色谱法对方中浙贝母、银花、瓜蒌进行定性鉴别;采用HPLC法测定橙皮苷的含量。结果橙皮苷的线性范围为418.2~2092.0 ng(r=0.9998),平均回收率为98.86%,RSD为0.80%。结论方法可行,重复性好,可作为该产品质量控制的方法。

【Abstract】 Objective To set up the quality standard for Kekezhi Koufuye.Methods Bulbus fritillariae Thunbergii,flos lonicerae japonicae and pericarpium trichosanthis were identified by thin-layer chromatography method.The contents of hesperidin in Kekezhi Koufuye were determined by HPLC.Results The linear range of hesperidin was 418.2~2092.0 ng(r=0.9998),the average recovery was 98.86%,and RSD was 0.80%.Conclusion The method is convenient,accurate and practicable.It can be used for the quality control of Kekezhi Koufuye.

【关键词】 咳咳止口服液; 橙皮苷; 高效液相色谱法;
【Key words】 Kekezhi Koufuye; hesperidin; HPLC;
  • 【文献出处】 中南药学 ,Central South Pharmacy , 编辑部邮箱 ,2007年02期
  • 【分类号】R286.0
  • 【被引频次】1
  • 【下载频次】87
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