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更昔洛韦联合苦参素治疗婴儿巨细胞病毒肝炎疗效观察
Combined treatment of ganciclovir and matrine for treatment of cytomeganlovirus hepatitis in infant
【摘要】 目的:探讨更昔洛韦(GCV)联合苦参素对婴儿巨细胞病毒(CMV)肝炎的疗效。方法:比较48例婴儿CMV肝炎用更昔洛韦联合苦参素治疗前后肝功能、肝脾大小变化以及CMV检测指标的转阴率。结果:肝功各项指标治疗前后差异显著(P<0.05),肝脾较治疗前明显缩小,差异显著(P<0.05)。血CMV-IgM、PCR-CMV-DNA转阴率分别为89.6%,80%。结论:更昔洛韦、苦参素注射液联合治疗CMV肝炎有较好疗效。
【Abstract】 Objective:To investigate the effect of ganciclovir and matrine in treating the infants with cytomegalovinus(CMV) hepatitis.Methods:Liver function、size of liver and spleen before and after treatment and negative rate of detected marks about CMV were respectively studied.Results:There was significant difference in marks of liver function、size of liver and spleen before and after treatment(P<0.05),negative rate of CMV-IgMCR-CMV-DNA was 89.6%,80% respectively.Conclusion: The effect of ganciclovir and matrine s in treating the infants with cytomegalovinus(CMV) hepatitis was certain.
- 【文献出处】 中国民康医学 ,Medical Journal of Chinese People’s Health , 编辑部邮箱 ,2007年16期
- 【分类号】R725.1
- 【被引频次】1
- 【下载频次】32