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更昔洛韦联合苦参素治疗婴儿巨细胞病毒肝炎疗效观察

Combined treatment of ganciclovir and matrine for treatment of cytomeganlovirus hepatitis in infant

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【作者】 盛凯付桂玲盛伟

【Author】 SHENG Kai,FU Gui-ling,SHENG Wei(Department of Rediatrics of the First Affiliated Hospital of Xinxiang Medical College,Xinxiang 453003,China)

【机构】 新乡医学院第一附属医院儿科河南省信阳市平桥区中医院 河南卫辉453100河南卫辉453100

【摘要】 目的:探讨更昔洛韦(GCV)联合苦参素对婴儿巨细胞病毒(CMV)肝炎的疗效。方法:比较48例婴儿CMV肝炎用更昔洛韦联合苦参素治疗前后肝功能、肝脾大小变化以及CMV检测指标的转阴率。结果:肝功各项指标治疗前后差异显著(P<0.05),肝脾较治疗前明显缩小,差异显著(P<0.05)。血CMV-IgM、PCR-CMV-DNA转阴率分别为89.6%,80%。结论:更昔洛韦、苦参素注射液联合治疗CMV肝炎有较好疗效。

【Abstract】 Objective:To investigate the effect of ganciclovir and matrine in treating the infants with cytomegalovinus(CMV) hepatitis.Methods:Liver function、size of liver and spleen before and after treatment and negative rate of detected marks about CMV were respectively studied.Results:There was significant difference in marks of liver function、size of liver and spleen before and after treatment(P<0.05),negative rate of CMV-IgMCR-CMV-DNA was 89.6%,80% respectively.Conclusion: The effect of ganciclovir and matrine s in treating the infants with cytomegalovinus(CMV) hepatitis was certain.

【关键词】 更昔洛韦苦参素巨细胞病毒肝炎
【Key words】 GanciclovirMatrineCytomeganlovirusHepatitis
  • 【文献出处】 中国民康医学 ,Medical Journal of Chinese People’s Health , 编辑部邮箱 ,2007年16期
  • 【分类号】R725.1
  • 【被引频次】1
  • 【下载频次】32
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