【摘要】 目的探讨染料注射法识别乳腺癌前哨淋巴结(SLN)活检时出现假阴性的原因。方法本组67例原发性乳腺癌患者,应用美蓝进行前哨淋巴结定位和活检,随后行腋窝淋巴结清扫(ALND),行SLN、腋淋巴结(ALN)病理学检查。结果67例乳腺癌患者中,64例(95.5%)检测到SLN,SLN预测ALN状态的敏感性为91.2%(31/34),准确性为91.0%(61/67),假阴性8.8%(3/34)。结论假阴性与原发肿瘤过大、肿瘤位置、年龄、病理学检查方法有关。更多还原

【Abstract】 Objective To investigate the cause of sentinel lymph node(SLN) biopsy false negative in breast cancer identified by vital blue injection to study the method of reducing the false negative rate.Methods 67 cases of primary mammary cancer were injected methylene blue to locate SLN and conduct biopsy.Axillary lymph node dissection(ALND) was conducted to examine the pathology of SLN and axillary lymph node(ALN).Results Of 67 cases,64 had detected SLN(95.5%) with sensitivity of 91.2%(31/34) and accuracy of 91%(61/67) and false negative of 8.8%(3/34).Conclusions The cause of false negative result is due to an extensive primary tumor,the position of tumor,age of the patients and the method of pathological examination.更多还原