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半胱胺对大鼠血脂代谢和抗氧化能力的影响

Effects of cysteamine on plasma lipids and anti-oxidant capacity of rats

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【作者】 朱建津乐国伟施用晖庞梁任爱春

【Author】 ZHU Jian-jin,LE Guo-wei,SHI Yong-hui,PANG Liang,REN Ai-chun(Food School of Southern Yangtze University,Wu-xi,Jiangsu 214036,China)

【机构】 江南大学食品学院江南大学食品学院 江苏无锡214036江苏无锡214036

【摘要】 在高能量/高脂日粮条件下,研究半胱胺对大鼠血脂和机体抗氧化能力的影响。结果表明:高能量/高脂日粮提高大鼠血浆TC,TG,TC/HDL-C,TG/HDL-C的水平;与高能量/高脂日粮组相比,添加半胱胺降低TC,TG,LDL-C,TC/HDL-C,TG/HDL-C和血糖的水平;高能量/高脂日粮不能诱导明显的氧化应激,添加半胱胺日粮对氧化还原指标影响不明显。表明高能量/高脂日粮能提高血脂水平,添加半胱胺可恢复血脂。

【Abstract】 This experiment was conducted to evaluate effects of cysteamine on plasma lipids and anti-oxidant of rats fed diets with higher energy /higher fat.The results showed that TC,TG,TC/HDL-C and TG/HDL-C were increased by feeding the diets with higher energy /higher fat as compared to normal energy diets.Addition of cysteamine in the diets decreased the levels of TC,TG,LDL-C,TC/HDL-C,TG/HDL-C,and blood sugar as compared with diets without cysteanine.Higher energy/higher fat was failed to induce oxidative stress in the experiments.Addition of cysteamine in the diets did not affect oxidaton-reduction index.The results indicated that the diets with higher energy/higher fat increased the contents of plasma lipids,whereas addition of cysteamine reduced the contents of plasma lipids.

【关键词】 半胱胺血脂抗氧化大鼠
【Key words】 cysteamineplasma lipidsanti-oxidantrats
【基金】 国家自然科学基金项目(30571347)
  • 【文献出处】 浙江农业学报 ,Acta Agriculturae Zhejiangensis , 编辑部邮箱 ,2007年01期
  • 【分类号】R341
  • 【被引频次】8
  • 【下载频次】177
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