【摘要】 目的:研究冠心病患者颈动脉粥样硬化与血管内皮舒张功能的临床意义。方法:采用高频超声测量冠心病组和对照组颈动脉斑块积分、斑块数、颈动脉内—中膜厚度(IMT)及血管内皮舒张功能(EDD%),并进行对比分析。结果:1.冠心病组颈动脉IMT、斑块积分及斑块数明显高于对照组,多支冠脉血管病变组明显高于单支病变组;2.冠心病组内皮舒张功能明显低于对照组,单支、双支病变组间无显著性差异。3.冠状动脉造影与颈动脉超声结果比较,以斑块存在为预测冠脉病变的阳性指标,敏感性为83%、特异性75%。结论:冠心病患者多合并血管舒张功能受损及颈动脉粥样硬化,高频超声探查颈动脉可预测冠状动脉病变的存在及严重程度。更多还原

【Abstract】 Objective: To investigate the clinical significance of the carotid arterosclerosis and endothelium-dependent dilation(EDD%) in coronary heart disease.Methods: The intima-media thickness(IMT),Crouse scores and numbers of plaque in carotid artery and endothelium-dependent dilation were measured by high-frequency ultrasound in patients with coronary artery disease and control group.The rersults were analyzed and compared.Results: There were significant differences in carotid artery IMT value,Crouse scores and numbers of plaque among the control,one-vessel stenosis and multi-vessel stenosis groups.There were significant differences in EDD% between control group and coronary artery disease group.There was no difference between one-vessel stenosis and multi-vessel stenosis groups.The sensitivity and specificity of predicting the coronary artery atherocslerosis by the carotid plaque were 83% and 75%.Conclusion: Carotid artery atherosclerosic lesions and EDD% can predict the existence and severity of the coronary artery atherosclerosis.更多还原