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雌二醇、促甲状腺素变化与产后抑郁症相关性研究

An analysis of estradiol and thyrotropinp postpartum depression

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【作者】 罗阳郑乐知莫朝辉甘邵隆周建伟

【Author】 LUO Yang~1,ZHENGlezhi~2,MO Zhao hui~2,GAN Shao long~2,ZHOU Jian wei~1(1 Nursing School of Central South University,2 The Third Xiang-ya Hospital of Central South University,Hunanchangsha 410013,China)

【机构】 中南大学护理学院中南大学湘雅附三医院中南大学护理学院 湖南长沙410013湖南长沙410013

【摘要】 目的探讨产后雌二醇(E2)、促甲状腺素(sTSH)变化与产后抑郁症状间的关系。方法对60例产妇在产后第7天内用放射免疫法检测产后雌二醇和促甲状腺素,同时用Ed ingburgh产后抑郁量表(EP-DS)、Beck抑郁量表(BD I)、一般健康问卷(GHQ)对产妇在产后7天内进行评定。结果产后E2及sTSH变化与EPDS量表得分呈负相关,P<0.05。结论产后雌激素及sTSH变化与产后抑郁的病因有关。

【Abstract】 Objective To study the changes of estradiol(E2),thyrotropinp(sTSH),and their relationships with postpartum depression.Methods The blood samples of 60 women were collected at 7nd day after childbirth,and the changes of E2,sTSH were assayed.Meanwhile these women were assessed with Edingburgh postnatal depressionscale(EPDS),Beck depression inventory(BDI) and general health questionnaire(GHQ) at 7nd day.Results The change of E2 and sTSH was negatively related to the scores of EPDS and BDI.Conclusions Changes of estradiol and thyrotropinp may play a role in postpartum depression.

【关键词】 雌二醇促甲状腺素产后抑郁
【Key words】 EstradiolthyrotropinpPostpartum depression
【基金】 湖南省科委中标课题(05SK3109)
  • 【文献出处】 中国医刊 ,Chinese Journal of Medicine , 编辑部邮箱 ,2007年01期
  • 【分类号】R749.4
  • 【被引频次】13
  • 【下载频次】247
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