Aim:To investigate the immunomodulatory effects of Ganoderma lucidum spores polysaccharides(GLSPs) on EC and S180 tumor-bearing mice.Methods:Effects of GLSPs on the humoral immune function and the endothelial system(RES) phagocytosis function of EC tumor-bearing mice were assessed.Moreover,CTL,TH cells and regulatory T cells in the peripheral blood lymphocyte of NK cells in S180 tumor-bearing mice were detected by flow cytometry and the activity of S180 tumor-bearing mice was examined.Results:GLSPs could el...