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伤疡愈凝胶的制备及质量标准研究
Study on Preparation and Quality Standard of Shangyangyu Gel
【摘要】 目的:制备伤疡愈凝胶并建立其质量标准。方法:以卡波姆940为凝胶基质制备伤疡愈凝胶。采用分光光度法在516nm波长处测定其含量;其它成分用薄层色谱法进行鉴别。结果:左旋紫草素浓度在8.048~40.24μg.mL-1范围内线性关系良好(r=0.9998),平均回收率为99.45%(RSD=1.13%)。结论:本制剂制备工艺简便,所建标准可用于质量控制。
【Abstract】 OBJECTIVE:To prepare Shangyangyu gel and establish a standard for its quality.METHODS:Shangyangyu gel was prepared using carbamer 940 as matrix.Its content was identified by spectrophotography,with the wavelength set at 516nm,and its other compositions were determined by TLC.RESULTS:The concentration of L-shikonin had good linear correlation with absorbance in the range of 8.048~ 40.24μ g· mL-1(r=0.999 8).The average recovery rate was 99.45%(RSD=1.13%).CONCLUSION:This method for preparation of Shangyangyu gel was simple in technique and the standard can be used for the quality control.
【Key words】 Shangyangyu gel; Preparation process; Quality control; Spectrophotography; TLC;
- 【文献出处】 中国药房 ,China Pharmacy , 编辑部邮箱 ,2007年09期
- 【分类号】TQ461
- 【被引频次】5
- 【下载频次】118