【摘要】 将300只1日龄公雏鸡随机分为3组,两组分别给予中药方Ⅰ和方Ⅱ(由石膏、苍术、黄柏、藿香分别按质量比1∶1∶1∶1和0.5∶1∶1∶1比例组成,按体重0.3 mg/kg的剂量饮水),对照组按照常规方法饲养。分别于雏鸡第7、21、35、49日龄时,每组随机抽取5只鸡剖杀,取腔上囊、脾、胸腺测定免疫器官指数和IL-2平均阳性表达率,以探讨中药复方对雏鸡免疫器官指数及其IL-2表达的动态影响。结果显示,随着用药时间的增加,中药方Ⅰ和方Ⅱ可显著(P<0.05)或极显著(P<0.01)提高腔上囊、脾和胸腺等免疫器官指数及其IL-2的平均阳性表达率,方Ⅰ对各免疫器官IL-2阳性表达率的影响最为显著(P<0.05)。证实该中药复方可促进雏鸡细胞免疫水平,增强其非特异性免疫功能,并促进免疫器官的发育。更多还原

【Abstract】 Three hundred 1-day-old male chickens were divided into 3 groups at random.GroupⅠ was taken orally 0.3 mg of the Chinese medicineⅠ,which was made up of powders of Gypsum fibrosum,dried Rhizoma atractylodis roots-and-rhizomes,dried Cortex phellodendribarks,and Herba agastachis rhizomes-and-leaves at the mass ratio of 1∶1∶1∶1,according 1 kg body weight,Group Ⅱ was taken orally 0.3 mg of chinese medicine Ⅱ,which was composed of the above-mentioned 4 ingredients at the mass ratio of 0.5∶1∶1∶1,per 1 kg body weight,and the control group was fed normally.On 7-,21-,35-and 49-day-old,5 chickens of each group were randomly taken to collect the bursa,spleen,thymus organs to detect the indexes of immune organs and IL-2 expression rates.The average IL-2 expression rates and indexes of immune organs were significantly enhanced by the Chinese materia medica(P<0.05 or 0.01).The results indicated that the Chinese materia medica could improve level of cellular immunity,enhance non-specific immunological function and promote growth of the immune organs.更多还原