不同方式吸入布地奈德治疗婴幼儿哮喘的疗效观察

【摘要】 目的:了解不同方式吸入布地奈德治疗婴幼儿哮喘的疗效。方法:将80例年龄小于3岁的婴幼儿哮喘患儿随机分成3组。A组:用雾化器吸入布地奈德混悬液;B组:使用面罩型筒式贮雾罐,吸入布地奈德气雾剂;对照组:不用吸入激素,常规治疗。在观察期的第1、3、6、12个月复诊,比较3组的临床症状评分、哮喘急性发作及药物使用的情况。结果:与对照组相比,A组和B组明显降低了日间、夜间症状评分,显著减少了哮喘的急性发作,减少了使用β2受体激动剂和全身激素的次数;而A组在观察期的第1、3、6个月的治疗效果比B组更明显(P<0.05),两组在第12个月的治疗指标的差异则无显著性(P>0.05)。结论:吸入布地奈德治疗可使哮喘得到长期的缓解;而使用雾化器吸入布地奈德混悬液,可以更早、更好地减轻哮喘症状,是婴幼儿哮喘的首选吸入方式。更多还原

【Abstract】 Objective:To evaluate the efficacy of inhaled Budesonide in the treatment of infant asthma.Methods:80 patients less than 3 years old were divided in three groups randomly,in group A the patients received Budesonide suspension aerosol inhalation therapy,in group B the patients received inhaled Budesonide therapy,in group C the patients received route treatment.The patients were followed 1,3,6,12 months after treatment,symptom assessment scores,acute episode of asthma and administration of medication were compared between two groups.Results:Compared with group C,symptom assessment scores became lower,acute episode of asthma reduced and use of β2 receptor agonist and steroid reduced in group A and B;after 1,3,6 months,the indicators observed in group A was better than in group B,but there was no difference between two group after 12 months.Conclusion:Budesonide inhalaton is effective in the treatment of asthma,in patients with infant asthma,Budesonide suspension aerosol inhalation should be the first choice of treatment.更多还原