【摘要】 目的评价国产电子阴道镜(型号JY2650)与光学阴道镜(型号YDJ99046)在宫颈上皮内瘤变(CIN)及人乳头瘤病毒(HPV)亚临床感染(SPI)诊断中的应用价值及临床意义。方法选择2005年7月至2006年1月昆明市延安医院妇产科收治的阴道镜及细胞学检查异常患者290例,同时应用国产电子阴道镜和光学阴道镜检查诊断,根据阴道镜图像定位取活检,均有病理诊断结果,对其进行对比研究。结果二者在CIN各级中的比较:(1)CINⅠ级:阴性预测、阳性预测及敏感性二者间差异有显著性意义(P<0·05)。(2)CINⅡ级:阴性预测与阳性预测差异有显著性意义(P<0·05)。(3)CINⅢ级:阴性预测和阳性预测二者间差异有显著性意义(P<0·05)。在SPI中的比较:阴性预测和阳性预测二者间差异有极显著性意义(P<0·01),敏感性差异有极显著性意义(P<0·01)。结论在CIN和SPI的临床诊断中,电子阴道镜的阴性预测值高;光学阴道镜的阳性预测值高、敏感性高;特异性两者相同。电子阴道镜在资料储存、随访、教学、科研中有一定可行性和实用性,优于光学阴道镜;而光学阴道镜阳性预测值高、敏感性高,对早期微小病灶的分辨优于电子阴道镜。更多还原

【Abstract】 Objective To evaluate the clinical value of domestically manufactured digital colposcope and optical colposcope in the diagnosis of cervical intraepithelial neoplasia(CIN)and the subclinical papillomavirus infection(SPI) of HPV.Methods A comparative study was carried out on the digital colposcope and optical colposcope in the diagnosis of CIN and SPI,by experimenting with 290 people who had been pathologically diagnosed from July 2005 to January 2006 in Kunming Yanan Hospital.Results The comparison of CIN in different levels was as follows:(1)CIN Ⅰ:The negative predictive value(NPV) and the positive predictive value(PPV) were with significant difference(P<0.05).(2)CIN Ⅱ:The NPV and the PPV were with significant difference(P<0.05).(3)CIN Ⅲ:The NPV and the PPV were with significant difference(P<0.05).The comparison of the SPI:the NPV and the PPV were with significant difference(P<0.01).The sensitivity were with extremely significant difference.Conclusion In the clinical diagnosis of CIN and SPI,the NPV of the digital colposcope is higher.The PPV and the sensitivity of the optical colposcope are higher.The specificity of both colposcopes is the same.Digital colposcope is more feasible and practicable in the field of scientific research,clinical diagnosis,information deposit,follow-up survey and education than optial colposcope.On the other hand,the PPV and sensitivity of optical colposcope are higher than digital colposcope,so it’s good at distinguishing tiny focus.更多还原