【摘要】 目的了解河南省郑州市围产儿神经管畸形发生水平、动态变化及流行病学特征。方法基于医院的监测方法,对全市14所监测医院1996～2004年出生缺陷监测中神经管畸形资料进行分析。结果神经管畸形总发生率为15.40/万,占出生缺陷总数的15.31%;3种神经管畸形发生率顺位依次是脊柱裂、无脑儿、脑膨出;神经管畸形发生率乡村高于城镇,女婴高于男婴,母亲年龄25～29岁组发生率最低,呈U型分布;其围产期死亡率为495.33‰,是总围产儿死亡率的39倍。结论郑州市围产儿神经管畸形发生率呈下降趋势。更多还原

【Abstract】 Objective To study the incidence,dynamic variable trend and the epidemiologyical characteristic of neural tube defects(NTDs)in Zhengzhou.Methods To analyze,the NTDs monitoring data of the fourteen participating hospitals in Zhengzhou from 1996～2004.Results The incidence of NTDs was 15.40 per 10,000,accounted for 15.31% of total birth defects.The precedence order was cleft spinabifida,anencephalus,cephalocele.The in cidence of NTDs incountry was higher than in town.Female baby’s prevalence was higher than male’s.Group aged 25 to 29 years was minimal birth defect The distributing showed a "u.".The case fatality rate of NTDs was 495.33 per 1,000 it was 39 times higher than the preinatal mortality rate.Conclusion Downtrend of NTDs incidence was observed in Zhengzhou from 1996 to 2004.更多还原