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血脂异常与蒙古族高血压关系

Relationship between hyperlipemia and hypertension in Mongolian people

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【作者】 唐惠滕国兴刘国玉佟伟军张永红

【Author】 TANG Hui,TENG Guo-xing,LIU Guo-yu,et al.Department of Epidemiology,School of Radiation Medicine and Public Health,Soochow University(Suzhou 215123,China)

【机构】 苏州大学放射医学与公共卫生学院流行病学教研室内蒙古通辽市疾病预防控制中心苏州大学放射医学与公共卫生学院流行病学教研室 苏州215123苏州215123

【摘要】 目的研究血脂异常与蒙古族高血压的关联性。方法对2 547名20岁~蒙古族居民进行血压等的测量,吸烟、饮酒等因素的调查及血脂的检测,采用单因素χ2及多因素非条件Logistic回归分析进行统计分析,以OR值作为评价关联的指标,用Mantel-Haenszelχ2趋势检验法分析甘油三酯(TG)与高血压间的剂量-反应关系。结果单因素分析结果显示,总胆固醇(TC)异常、甘油三酯(TG)异常、低密度脂蛋白胆固醇(LDL-C)异常与高血压相关联(P<0.001)。经Logistic回归模型分析,调整了年龄、性别、体质指数(BMI)、腰臀比(WHR)、血糖和高血压家族史等因素后,TC异常及LDL-C异常与高血压的关联差异无统计学意义(P>0.05),而TG异常与高血压之间的关联差异仍有统计学意义(OR=1.579,95%CI=1.232~2.024)。剂量-反应关系分析结果显示,蒙古族高血压的患病危险性有随着TG的升高而增高的趋势。结论TG异常可能是蒙古族高血压的独立危险因素,高血压的患病危险有随TG水平升高而增高的趋势。

【Abstract】 Objective To investigate correlation between hyperlipemia and hypertension in Mongolian people.Methods The blood pressure and so on were measured and factors including smoking cigarette and alcohol intake,and blood lipids for 2?547 Mongolian people aged 20 and elder were investigated,the statistic analysis were done by using chi square test and multiple logistic model,and correlations were evaluated by using odd ratio(OR),dose-effect relations between TG and hypertesion were analyzed by means of Mantel-Haenszel chi square trend test.Results Single factor analysis showed that high total cholesterol(TG),high triglyceride(TG),high low density lipoprotein-cholesterol(LDL-c) were all correlated with hypertension.After adjustment for age,gender,body mass index(BMI),waist-hip ratio(WHR),blood glucose and family history of hypertension by multiple logistic model,there were no correlations between high TC,high LDL-c and hypertension(P>0.05).There were still a significant correlation between high TG and hypertension((OR 1.579,95%CI 1.232~2.024).Results of dose-effect analysis showed that the risk of prevalence for hypertension increased with TG level.Conclusion High TG may be a independent risk factor of hypertension in Mongolian people,and there was a tendency that the risk of prevalence of hypertension increased with TG level.

【关键词】 蒙古族高血压血脂异常
【Key words】 mongolianhypertensionhyperlipemia
【基金】 国家自然科学基金(30471484)
  • 【文献出处】 中国公共卫生 ,Chinese Journal of Public Health , 编辑部邮箱 ,2007年01期
  • 【分类号】R589;R544.1
  • 【被引频次】38
  • 【下载频次】246
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