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宫颈糜烂高危因素的病例对照研究

Case-control study on risk factors of cervical erosion

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【作者】 徐又先濮德敏

【Author】 XU You-Xian,PU De-Min.Department of Obstetrics & Gynecology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Hubei,China

【机构】 华中科技大学同济医学院附属同济医院妇产科华中科技大学同济医学院附属同济医院妇产科 430030430030

【摘要】 目的:探讨人群宫颈糜烂发生的相关危险因素。方法:采用病例对照的研究方法,对141例宫颈糜烂患者和137例宫颈光滑者对照进行年龄、生殖道病原微生物、婚育史、性行为等因素研究。结果:在单因素分析的基础上进行多元Logistic回归分析,最终引入回归方程的变量为年龄、首次性交年龄、分娩方式、产次、HPV感染,而首次发生性行为年龄、结婚和孕育年龄、孕产次等生殖因素,与宫颈糜烂发生的危险性呈剂量-反应关系。结论:年龄、首次发生性行为年龄小、HPV感染和孕产次是宫颈糜烂发生的高危因素。

【Abstract】 Objective:To explore the risk factors of cervical erosion.Methods:A case-control study was conducted in 141 cases with cervical erosion and 137 cases with smooth cervix uteri as controls interviewed using a questionnaire,including baseline information,pathogen in the vagina,marital and pregnancy histories,sexual behavior,etc.Results:Based on monovariate analysis results,multivariate non-conditional logistic analysis was used,age,age at first intercourse,partal method,parity,the HPV infection were associated with cervical erosion.Meanwhile,first intercourse age,the marriage age,pregnancy and birth age,gravidity and parity expressed the relationship of dosage-response with cervical erosion.Conclusion:The relation risk of cervical erosion enhanced with decreasing age at first intercourse,age of 26~35,HPV infection,and with increasing number of gravidity and parity.

  • 【文献出处】 中国妇幼保健 ,Maternal and Child Health Care of China , 编辑部邮箱 ,2007年17期
  • 【分类号】R711.32
  • 【被引频次】16
  • 【下载频次】137
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