【摘要】 目的:分析反复流产夫妇的异常核型发生率、形成原因及其染色体分析的临床价值。方法:对114对反复流产夫妇行外周血染色体分析。结果:检出异常染色体核型13例,占受检夫妇人数的5·7%,异常核型中,平衡易位最多,占异常总数的76·92%,其中相互易位10例,罗伯逊易位3例;其次为倒位,为6号、9号以及Y染色体的臂间倒位。结论:对于不明原因的反复流产夫妇,染色体分析必须作为常规的检测方法。更多还原

【Abstract】 Objective:To analyze the incidence and reasons of abnormal karyotypes and clinical value of chromosome analysis in recurrent spontaneous abortion (RSA).Methods:Chromosome analysis was performed on 114 couples with RSA.Results:13 cases of abnormal karyotypes were detected (5.7%).Balanced translocations had the most abnormalities (76.92%), including 10 balanced reciprocal translocations and 3 balanced Robertsonian translocations. The other types of abnormal karyotpyes were balanced pericentric inversions, affected chromosome 6, 9 and Y.Conclusion:Chromosomal analysis should be carried out routinely in every couple with unexplained failure of reproduction.更多还原