【摘要】 以DMF作溶剂,在四丁基氟化铵(TBAF)存在下,对甲基苯基三甲硅基醚(1)和4,4′-二氯二苯砜(2)于100℃反应1h,合成了4,4′-二(4-甲基苯氧基)二苯砜(3),产率为92%;加入催化量的N-溴代丁二酰亚胺(NBS)并在光照条件下,与氧气反应得到中间体-4,4′-二(4-羧基苯氧基)二苯砜(4),其产率达90%;将化合物4与二氯亚砜反应合成目标产物4,4′-二(4-氯甲酰基苯氧基)二苯砜(5),总收率为74.5%(以对甲基苯基三甲硅基醚为基准计算)。更多还原

【Abstract】 The reaction of p-methylphenyltrimethylsilyl ether(1) with 4,4’-dichlorodiphenylsulfone(2) in DMF and in the presence of tetrabutylammonium fluoride(TBAF) at 100 ℃ for 1 h afforded 4,4’-bis(4-methylphenoxy)diphenyl sulfone(3) in a yield of 92%.Then compopund 3 was oxidized in air to the corresponding intermediate 4,4’-bis(4-carboxyphenoxy)diphenyl sulfone(4) in a yield of 90% in the presence of a catalytic amount of N-bromosuccinimde(NBS) under photoirradiation.Subsequently the reaction of compound 4 with thionyl chloride yielded target compound 4,4’-bis(4-chloroformylphenoxy)diphenylsulfone(5) in a overall yield of about 74.5%(based on compound 1).The present method has the advantages of readily availability of starting materials,mild reaction conditions,convenient manipulation and good yields.更多还原