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正交实验法优选黄芪蛰虫口服液的制备工艺

Research on Extract Technology of Huangqi Zhechong Decoction with Orthogonal Design Methods

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【作者】 席枝侠党双锁王美纳邹晶

【Author】 XI Zhi-xia, DANG Shuang-suo , WANG Mei-na, ZOU Jing(Department of Pharmacy, the Second Hospital of Xi’an Jiaotong University, 710004,China)

【机构】 西安交通大学第二医院药剂科西安交通大学第二医院药剂科 710004710004

【摘要】 目的优选黄芪蛰虫口服液的最佳提取工艺。方法采用正交实验法对煎煮过程中水的用量、煎煮次数、煎煮时间3个因素选取3个水平,考察黄芪甲苷与水溶性多糖含量2项指标,用直观法和方差分析法分析结果。结果最佳提取工艺为A3B2C1,即煎煮水量为药材的20倍,煎煮次数为2次,煎煮时间为2h。结论该方法优选最佳方案能保证黄芪蛰虫口服液的质量。

【Abstract】 Objective To seek out the optimum extract technology of huangqi zhechong decoction. Methods Three levels in each of three factors( amount of water, decoction frequency and duration of decoction) were selected with orthogonal design. The conteats of astragaloside Ⅳ and polysaccharides served as indexes. Results The optimum extracting conditions were as follows. The amount of water was twenty times that of the drug, the decoction frequency was two ,and the duration of decoction was two hours. Conclusion This method of optimum design can guarantee the quality of huangqi zhechong decoction.

【基金】 陕西省科技攻关项目(基金编号:2002K11-G7)
  • 【文献出处】 医药导报 ,Herald of Medicine , 编辑部邮箱 ,2007年01期
  • 【分类号】TQ461
  • 【被引频次】2
  • 【下载频次】203
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