【摘要】 阿尔茨海默病(AD)是最常见的痴呆类型,主要病理特征是β-淀粉样蛋白聚集形成老年斑,tau蛋白聚集形成神经纤维缠结,脑内神经元大量丢失。AD的发病机制有多种学说,但越来越多的研究表明免疫炎性反应与AD的发病及进展有关。本文对小胶质细胞、炎性因子、补体等在AD中的作用予以综述。更多还原

【Abstract】 Alzheimer’s disease is the most type of dementia,of which the main pathological feature are forming of senile plaque resulting from aggregation of β-amyloid,neurofibrillary tangle by aggregation of tau protein and loss of quantity of nervous cells.Although there are many hypothesis about pathogenesis of AD,more and more studies showed that immune inflammatory reaction is related to the genesis and development of AD.This article reviews the effects of gitter cell,inflammatory factor and complement in AD.更多还原