【摘要】 FADD是Fas系统的一个信号连接蛋白,是死亡受体与胞浆成分之间联系的纽带,介导细胞凋亡。恶性转化的肿瘤细胞是因为生长失控导致的过度增殖,肿瘤细胞凋亡机制受到抑制而导致肿瘤细胞不能进行正常凋亡并且清除。FADD作为凋亡信号的连接蛋白,在恶性肿瘤的发生、发展过程中起着重要的作用,现就FADD与恶性肿瘤的关系进行综述。更多还原

【Abstract】 FADD is a signal connectin in Fas-FasL apoptotic path,which is the vinculum between death receptor and endochylema elements mediating cell apoptosis.Tumour cells with malignant transformation is its over proliferation resulting from over growth out of control as wel as its abnormal apoptosis or clear out resulting from restrained mechanism of cell apoptosis.As a connectin in apoptosis signal,FADD plays an important role in genesis and development of malignant tumours.This article is a review about relationship between FADD and malignant tumours.更多还原