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广州市健康人群EB病毒-IgA抗体的调查

Survey on Epstein Barr Virus IgA/VCA Antibody Level of Health Population in Guangzhou

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【作者】 张伟狄飚鲁恩洁刘远谢华萍

【Author】 ZHANG Wei DI Biao LU En-jie LIU Yuan Guangzhou Centers for Disease Control and Prevention,Guangzhou 510080,China

【机构】 广州市疾病预防控制中心广州市疾病预防控制中心 510080 广东省510080 广东省

【摘要】 目的了解EB病毒VCA-IgA在健康人群中的抗体水平。方法EB病毒VCA-IgA,测定用酶联免疫法。结果显示本市某单位707例健康人群EB病毒VCA-IgA普查,阳性者18例,检出阳性率为2.55%。其中男性12例,占阳性总数的66.67%,女性6例,占阳性总数的33.33%。男女比例为2:1。VCA-IgA抗体阳性数集中在1:20~1:40之间,共有14例,占阳性总数的77.78%,1:160滴度只有1人。符合文献的鼻咽癌发病率男、女性别之比全国平均为1.96:1,南方五省为2.03:1的报道。结论EB病毒VCA-IgA检测对NPC的辅助诊断具有重要价值。

【Abstract】 Objective To determine the antibody level of Epstein Barr virus IgA/VCA of health population in Guangzhou.Methods Epstein Barr virus IgA/VCA was detected with ELISA.Results A total of 707 healthy in- dividuals from an institute in Guangzhou were detected for Epstein Barr virus IgA/VCA with ELISA.18 persons were Epstein Barr virus IgA/VCA-antibody positive(2.55%),among them the male was 12(66.67%)and the fe- male was 6(33.33%).The ratio of male and female was 2:1.Most of the antibody level of Epstein Barr virus IgA/ VCA was from 1:20 to 1:40,and the amount was 14(77.78%).Only one person’s antibody level was 1:160.The results were corresponded with the report that in nasopharyngeal carcinoma(NPC)patients,the ratio of male and female was 1.96:1 in all the country and 2.03:1 in 5 provinces of south China.Conclusion The detection of IgA/ VCA may have an important value in aiding diagnosis of NPC.

【关键词】 EB病毒鼻咽癌VCA-IgA抗体
【Key words】 Epstein barr virusNasopharyngeal carcinomaIgA/VCA
  • 【文献出处】 医学动物防制 ,Chinese Journal of Pest Control , 编辑部邮箱 ,2007年07期
  • 【分类号】R739.63
  • 【被引频次】16
  • 【下载频次】129
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