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度洛西汀治疗抑郁症随机双盲对照研究

A double-blind study of duloxetine in the treatment of depression

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【作者】 李娜; 徐治; 赵兴蓉; 许秀峰;

【Author】 LI Na,XU Zhi,ZHAO Xing -rong,et al.(The First Affiliated Hospital of Kunming Medical College,Kunming 650032 China)

【机构】 昆明医学院第一附属医院精神科; 昆明医学院第一附属医院精神科 云南昆明650032; 云南昆明650032;

【摘要】 <正>度洛西汀是一种新型抗抑郁药[1],为研究其对抑郁症的临床疗效及安全性,以氟西汀为对照,现将结果报告如下。对象和方法研究对象:为本院2005年9

【Abstract】 Objective To evaluate the efficacy and safety of duloxetine in the treatment of depression. Method 68 patients with depression were randomly divided into study group(duloxetine)and control group(fluxetine),and treated for 6 weeks.Efficacy and side effects were assessed with HAMD,HAMA,CGI-SI,and AE respectively before and after treatment.Results The efficacy was similar for the two drugs.The efficacious rate was 85.3% and the adverse events rate was 41.2% for duloxetine.No significant difference was found in the adverse events between the two groups.Conclusion Duloxetine is an effective drug for depression,with good tolerance.

【关键词】 度洛西汀; 氟西汀; 抑郁症;
【Key words】 Duloxetine; Fluxetine; Depression;
  • 【文献出处】 云南医药 ,Medicine and Pharmacy of Yunnan , 编辑部邮箱 ,2007年04期
  • 【分类号】R749.4
  • 【被引频次】9
  • 【下载频次】89
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