节点文献
3-芳氧基-6-(3,5-二甲基-1H-吡唑-1-基)哒嗪的合成及生物活性
Synthesis and Biological Activity of 3-Aryloxy-6-(3,5-dimethyl-1H-pyrazol-1-yl)-pyridazine
【摘要】 为了寻找高活性的先导化合物,以3,6-二氯哒嗪为原料,经过三步反应,合成了一系列未经文献报道的3-芳氧基-6-(3,5-二甲基-1H-吡唑-1-基)哒嗪.所有新化合物的结构均经过1H NMR,IR,LC-MS和元素分析确认.初步的生物活性测试表明,所合成的化合物都有一定的除草活性.
【Abstract】 In order to find highly active lead compounds, a series of new pyridazine derivatives have been synthesized using 3,6-dichloropyridazine as starting material by a three-step synthetic route. The structures of all compounds were confirmed by 1H NMR, IR, LC-MS spectra and elemental analysis. The preliminary bioassay results showed that all of the compounds possessed some extent herbicidal activity.
【基金】 国家自然科学青年基金(No.20302004)资助项目.
- 【文献出处】 有机化学 ,Chinese Journal of Organic Chemistry , 编辑部邮箱 ,2007年06期
- 【分类号】TQ450.1
- 【被引频次】6
- 【下载频次】311