【摘要】 在对叔丁基硫杂杯[4]芳烃的下缘1,3位引入芳醛基,合成了硫杂杯[4]二醛基衍生物2.化合物2与苯胺、水杨酰肼、烟酰肼、异烟酰肼等通过席夫碱缩合反应得到新型硫杂杯[4]氮杂衍生物3a～3d,产率分别为83%,80%,77%和79%.化合物2与邻苯二胺、乙二酰肼、丙二酰肼、己二酰肼等通过“1+1”分子间缩合得到新型1,3-桥联硫杂杯[4]氮杂衍生物4a～4d,产率53%,51%,59%和66%.新化合物的结构经IR,1HNMR,MS和元素分析等证实.更多还原

【Abstract】 Thiacalix[4]arene bi-benzaldehyde derivative 2 was synthesized by introducing benzaldehyde groups on 1,3-position of p-tert-butylthiacalix[4]arene. Reacting compound 2 with aniline, salicylic hy-drazide, nicotinic hydrazide or isonicotinic hydrazide gave series of novel thiacalix[4]arene aza derivatives 3a～3d by the Schiff-base condensation in the yields of 83%, 80%, 77% and 79%, respectively. Treatment compound 2 with o-phenylendiamine, oxalyl dihydrazide, malonic dihydrazide and adipic dihydrazide af-forded novel bridged thiacalix[4]arene aza derivatives 4a～4d by “1+1” condensation in the yields of 53%, 51%, 59% and 66%. The structures of all new compounds were characterized by IR, ESI-MS, 1H NMR spectra and elemental analyses.更多还原