【摘要】 目的探讨治疗妊娠早期细菌性阴道病的意义及方法。方法将282例早期妊娠合并细菌性阴道病病例随机分成5组。A组:未治疗组;B组:口服甲硝唑组;C组:阴道内应用甲硝唑组;D组:阴道内应用定君生组;E组:口服甲硝唑同时阴道内应用定君生。比较未治疗组与治疗组的难免流产、早产、胎膜早破、产褥感染的发生率,及4个治疗组间的治愈率、总有效率、达到治愈标准所需疗程数及复发率。结果治疗组的难免流产、早产、胎膜早破、产褥感染的发生率较未治疗组(A组)低(P<0.05);治愈率及总有效率(治愈率+有效率)B、C、D三组间比较差异无显著性(P>0.05),而E组则高于B、C、D三组(P<0.05);达到治愈标准所需疗程数及复发率,B、C、D三组间比较差异无显著性(P>0.05),而E组明显低于B、C、D三组(P<0.05)。结论对于妊娠早期发生的细菌性阴道病,积极、及时治疗有利于改善妊娠结局;单一应用甲硝唑或定君生,或联合使用定君生和甲硝唑,均为有效的治疗方法,但联合用药疗效更佳。更多还原

【Abstract】 Objective To study the effect of treatment of bacterial early pregnancy.Methods 282 early pregnancy women with bacterial vaginosis were divided into 5 groups randomly.Group A:no treatment.Goup B:roal metronidazol.Goup C:endovaginal metronidazol.Group D:endovaginal lactobacillus.Group E:oral metronidazole and endouaginal lactobacillus.Comparing the rate of inevitable abortion,premature delivery,premature rupture of membranes(Prom),acute and emergent disease and curative rate,response raet,number of cycles received and the recurrence rate among groups.Results The significant defference was found between treated group and no ones(P <0.05).There was no evident correlation to curative rate,total response rate,number of cycles received and the recurrence rate among group B.C and D(P >0.05).Group E was distinctly to group B.C and D(P <0.05).Conclusion Pregnancy outcomes can be improved if the treatment of bacterial vaginosis developed in early pregrancy.Only one medicine is used and combined use of drugs are effectiveness,but the latter is brtter.更多还原