【摘要】 目的:探讨事件相关电位N400在癫痫诊断中的临床意义。方法:2003年1月～2007年1月我科收治的30例癫痫患者作为观察组,33例正常健康体检者作为对照组,采用MEB-9104K诱发电位仪检测事件相关电位N400,然后进行对比分析。结果:癫痫组在发病后1天、15天N400的潜伏期较对照组长(P<0.05),而在30天时与对照组差异无显著性(P>0.05)。癫痫组N400的平均波幅在第1、15、30天分别较对照组低(P<0.05)。结论:N400电位在癫痫中的应用将为诊断该病提供客观有效的实验室依据。更多还原

【Abstract】 Objective:To explore the clinical meaning of event related potentials(N400)in epilepsy.Methods:From Jan 2003 to Jan 2007,33 normal people as control group and 30 epilepsy patients in study group were detected by ME-9104k evoked potential detector,and then contrasted and analyzed respectively.Results:At different stages,average wave crest latent period of N400 in study group was longer than that of control group during pretherapy and on therapy(P<0.05),but no significant difference in the thirtieth day(P>0.05).While average amplitude of wave N400 in the study group was significantly shorter than that of control group during different stage of treatment(P<0.05).Conclusion:Event related potentials(N400)could provide objective and effective laboratory data in the diagnosis of epilepsy.更多还原