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微量白蛋白尿与冠状动脉病变严重程度的关系
The relationship between microalbuminuria and the serious degree of coronary heart disease
【摘要】 目的:探讨微量白蛋白尿(MA)与冠心病冠状动脉病变严重程度的关系。方法:经冠状动脉造影确诊的冠心病患者(冠心病组)81例和非冠心病患者(对照组)54例,检测两组的尿白蛋白滤过率(UREA)及相关血脂、血糖等生化指标。结果:冠心病组尿白蛋白滤过率水平显著高于时照组(127.67±61.43)μg/min与(62.55±54.71)μg/min(P<0.01);相关分析显示尿白蛋白滤过率与冠脉狭窄指数呈正相关(P<0.05)。多元Logistic回归分析显示冠心病的发病与尿白蛋白滤过率有关。结论:微量白蛋白尿水平与冠心病冠状动脉病变程度密切相关,微量白蛋白尿是冠心病的独立危险因素之一。
【Abstract】 Objective:To explore the relationship between microalbuminuria(MA) and the serious degree of coronary heart disease.Methods:One hundred thirty five patients were included in the study: normal control group(n=54) and cornoary heart disease(CHD) group(n=81). All patients were diagnosised by cornoary arteriongraphy. The lvevels of urinary albumin filtration rate(UREA),blood-fat and blood glucose were analyzed respectively. Results:The levels of UREA in CHD group were significantly higher than those of normal control group(P<0.01). Correlation analysis showed that the levels of UREA are positively correlated with coronary artery stenosis exponent(P<0.05). Muliple regression analysis(Logistic) showed the morbidity of CHD were correlated with UREA. Conclusion:The levels of UREA are closely correlated with the serious degree of coronary heart disease,MA is the independent risk factor in CHD.
- 【文献出处】 现代医药卫生 ,Modern Medicine & Health , 编辑部邮箱 ,2007年11期
- 【分类号】R541.4
- 【被引频次】15
- 【下载频次】76