【摘要】 目的观察卡维地洛对充血性心力衰竭(CHF)左心功能的影响。方法患冠心病、原发性高血压、扩张型心肌病的CHF患者共174例随机分为治疗组和对照组各87例,治疗组在强心、利尿、血管紧张素转换酶抑制剂(A-CEI)治疗的基础上,每天给卡维地洛6.25~50mg口服治疗,疗程24周。作治疗前、后NYHA分级、心功能的对照。结果治疗后NYHA分级、心功能均得到改善。结论卡维地洛治疗CHF 24周后,能抑制CHF的恶化,改善心功能,改善生活质量。更多还原

【Abstract】 Objective To observe the therapeutic effects of carvedilol on left ventricle heart function in congestive heart failure(CHF).Methods 87 patients with congestive heart failure caused by coronary heart disease,primary hypertension,dilated cardiomyopathy were treated with carvedilol(3.125～25mg,Po,bid),in combination with positively inotopic agents and diuretics.The treatment sustained for three months.The following data were observed: NYHA class,LVEF,ΔD%,CI,E/A,C/T.Results This kind of treatment obtained reducion in ventricular remodeling and improvement in heart function,not only systolic but also diastolic function.Conclusions Carvedilol is an effective agent in the treatment of CHF.更多还原