【摘要】 目的探讨左心房容积指数(LAVI)与急性心肌梗死(AMI)预后之间的关系。方法选取收治的AMI病例312例,于急性期行超声心动图检查,测左心房容积、左心室的收缩和舒张功能,左心房容积通过体表面积来校正,将观察者按LAVI分为两组,即LAVI>30ml/m2共168例(占54%)和≤30ml/m2共144例(占46%)两组,自病例入院开始观察,若病例死亡观察结束。结果在平均36个月(0~60月)的观察随访过程中,共有50例死亡,其中LAVI≤30ml/m2死亡14例,LAVI>30ml/m2者死亡36例,P<0.001。LAVI是AMI病例预后的一个重要和独立危险因素(LAVI每增加1ml/m2,相对危险度为1.04,95%可信区间为1.03~1.06,P<0.001)。结论LAVI增大是AMI病例预后的一个独立危险因素,能够提供关于心肌梗死病例预后的信息,它和射血分数一起可以大大提高对心肌梗死病例预后的预测。更多还原

【Abstract】 Objective To explore the relation between left atrial volume index(LAVI) and prognosis of acute myocardiac infarction(AMI).Methods Three hundred twelve patients with AMI who had echocardiogram with assessment of left ventricular(LV) systolic and diastolic function and measurement of left atrial(LA) volume.The LA volume was corrected for boby surface area,and the population was divided into group A(LAVI(30ml/m2) and group B(LAVI≤30ml/m2).Results There were 168 patients in group A and 144 patients in group B.Compared with patients in group B,patients in group A were older and had a greater prevalence of hypertension,diabetes,hyperlipidemia and previous revascularization (P<0.05),but LV volume was larger and LVEF less.During follow-up 36(rang 0 to 60) months,50 patients were died.There were no different in the treatment,36 patients died in group A and 14 patients in group B(P<0.01).LAVI was a powerful predictor of mortality and remained an independent predictor(hazard ratio 1.04 per 1ml/m2 change,95% CL 1.03 to 1.06).Conclusions LAVI is a powerful predictor of mortality after AMI,Its reliability will be greatly improved if united with LV ejection function.更多还原