【摘要】 目的评价骨源性碱性磷酸酶在儿童营养性佝偻病早期诊断及治疗中的应用,为防治儿童营养性佝偻病提供依据。方法对2148名0~6岁儿童应用骨源性碱性磷酸酶(BALP)检测试剂盒进行检测。对部分BALP检测结果异常者进行治疗后复查,观察BALP值的变化情况。结果BALP>200U/L检出率为73.5%;以BALP≥250U/L为临床诊断界限值,异常检出率为35.4%。134例病例用维生素D制剂治疗后复查,有效率为79.9%。结论BALP检测对儿童营养性佝偻病诊治有重要的临床价值。更多还原

【Abstract】 Objective To evaluate the applicative valuation of bone alkaline phosphatase (BALP) in the early diagnoses and the treatment to the nutritive rickets in the children. Methods A total of 2 148 children(aged 0-6) were examined by BALP test. After giving treatment to parts of abnormal cases, examination was conducted to observe BALP changes. Results About 73.5% of the children were unusual in BALP(>200 U/L). With BALP≥250 U/L as the clinical diagnosed standard, 35.4% of the children were diagnosed to the rickets. After giving Vitamin D tablet, the effective rate was 79.9% among 134 cases. Conclusion BALP is effective to the diagnosis and treatment to children’s nutritive rickets.更多还原