【摘要】 [目的]探讨急性有机磷农药中毒(AOPP)患者血、尿β2-微球蛋白(β2-M)的变化及意义。[方法]用放射免疫分析法检测71例AOPP患者血、尿β2-M,并与45例正常对照比较。[结果]AOPP患者血、尿β2-M均高于正常对照,差异有统计学意义(P﹤0.0005),且中毒愈重,增高愈明显。[结论]检测AOPP患者血、尿β2-M对早期肾损害的诊断具有重要意义。更多还原

【Abstract】 ObjectiveTo explore the changes and significance of serum and urinary β2-microglobulin(β2-M)in patients with acute organophosphorus pesticide poisoning(AOPP).MethodsSerum and urinary β2-M were tested with radio immunoassay in 71 patients with AOPP and compared with 45 cases of normal controls.ResultsSerum and urinary β2-M of AOPP patients were higher than those of normal controls,the difference was statistically significant(P﹤0.000 5),and the increase of serum and urinary β2-M had positive correlation with the degree of poisoning.ConclusionsMeasurement of serum and urinary β2-M in patients with AOPP is important for early diagnosis of kidney damage.更多还原