【摘要】 目的观察左心交感神经切除术对先天性长Q-T间期综合征的疗效。方法对4例先天性长Q-T间期综合征患者行左心交感神经切除术,观察手术前后心电图及临床症状的变化。结果4例手术均成功,术后Q-TC间期(0.562±0.052s)较术前(0.578±0.039s)略缩短,差异无显著性意义(P>0.05);室性心律失常明显减少,T波由切迹、双峰变为光滑。随访24～30个月仅1例晕厥复发。结论左心交感神经切除术治疗药物不能控制的先天性长Q-T间期综合征患者是有效的,但发病机制不同者疗效不一。更多还原

【Abstract】 Objective To observe effect of left cardiac sympathectomy on congenital long QT syndrome(LQTS). Methods Left cardiac sympathectomy was performed in 4 congenital LQTS patients. ECG and clinical symptoms were assessed before surgery and during follow-up. Results QTC interval was shortened from 0.578±0.039s before to 0.562±0.052s after surgery, but the difference was no significant (P>0.05).Ventricular arrhythmias reduced obviously. T wave turned to smooth from notch and double hump. One case had syncope relapsed during follow-up period of 24 to 30 months. Conclusion Left cardiac sympathectomy maybe effective for congenital LQTS which is resistant to drug therapy.更多还原