【摘要】 目的:探讨高血压合并高血脂症患者血清锌(Zn)、铜(Cu)、铁(Fe)、钙(Ca)、镁(Mg)、钾(K)、钠(Na)含量变化及其临床意义。方法:采用原子吸收分光光度计、全自动生化分析仪和试剂盒分别检测了44例高血压合并高血脂症患者、42例单纯高血压病患者血清Zn、Cu、Fe、Ca、Mg、K、Na及胆固醇(Ch)、甘油三脂(TG)、载脂蛋白A-I(Apo A-I)、载脂蛋白B(Apo B),并与30例正常对照组进行比较分析。结果:高血压合并高血脂症患者的血清Zn、Fe、Mg、Na、Na/K、Zn/Cu及Ch、TG、Apo B均明显高于单纯高血压组和对照组,血清Cu、Ca、K、Ca/Mg及Apo A-I、Apo A-I/Apo B则低于单纯高血压组及对照组,血清Cu、Ca、K、Ca/Mg及Apo A-I、Apo A-I/Apo B比值与收缩压(SBP)和舒张压(DBP)呈负相关,而Zn、Mg、Na、Na/K和Zn/Cu则呈显著正相关;Cu、K、Ca、Ca/Mg与Ch和TG均呈显著负相关,而Zn、Fe、Mg、Na、Na/K、Zn/Cu与Ch、TG、Apo B均呈显著正相关;SBP和DBP与Ch和TG均呈显著正相关。结论:血清中Zn、Cu、Fe、Ca、Mg、K、Na含量的变化与高血压合并高血脂症的发生发展有密切的关系。更多还原

【Abstract】 Objective: To study the changes of serum zinc(Zn),copper(Cu),iron(Fe),calcium(Ca),magnesium(Mg),potassium(K) and sodium(Na) in hypertension complicated with hyperlipemia and their significance.Methods: The serum levels of Zn,Cu,Fe,Mg,Na,K,Na,cholesterol(Ch),triglyceride(TG),apolipoprotein A-I(Apo A-I) and apolipoprotein B(Apo B) were determined in 44 patients with hypertension complicated with hyperlipemia,42 patients with hypertension(HP) and 30 healthy controls by atomic absorption spectrophotometry,automatic biochemical analytical instrument and reagent kit.Results: It was found that the contents of Zn,Fe,Mg,Na,Na/K,Zn/Cu,Ch,TG and Apo B in hypertension complicated with hyperlipemia were significantly higher than in HP and control,while Cu,Ca,K,Ca/Mg,Apo A-I and Apo A-I/Apo B were significantly lower than in HP and control.Conclusion: It is suggested that hypertension complicated with hyperlipemia is closely related with Zn,Cu,Fe,Mg,Na,K and Na.更多还原