【摘要】 目的:研究高血压患者尿液中微量蛋白的浓度变化,以及时诊断和防治高血压早期肾损伤。方法:采用散射比浊法检测尿微量白蛋白(MA)、α1-微球蛋白(α1-MG)、转铁蛋白(TRF)和免疫球蛋白(IgU),尿蛋白定性采用干化学试带法。结果:高血压患者肾损伤时尿蛋白定性阴性,尿中MA、α1-MG、TRF与正常对照组有显著性差异,IgU无显著性差异。随着病程的延长,MA、α1-MG的阳性率逐渐增高。结论:诊断高血压患者早期肾损伤,采用尿微量蛋白检测比尿蛋白定性更敏感。更多还原

【Abstract】 Objective: To study the value of Urine Micro-protein(UMP) of hypertension patients in the diagnosis and treatment of the early hypertensive nephropathy.Method: Detected the value of microalbmin-Uria(MA) , α1-microglobulin (α1-MG) , transferrin(TRF) , urinary Ig (IgU) with scattering nephelometry and proteinuria with dry chemistry test. Results: Urine protein was negative in hypertensive patients with nephropathy.The level of MA , α1-MG , TRF were significantly different(P<0.01) between hypertension patients and normal controls;The level of IgU showed no significant difference between two groups(P>0.05) .Conclusion: Urine micro-protein examination can be more sensitive than protein qualitation test in diagnosising nephrotic damage of hypertensive patients.更多还原