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中药超微粉对早期断奶仔猪白细胞分类和抗氧化功能的影响

Effects of Chinese Herbal Ultra-Fine Powder as Dietary Additive on Blood Total and Differential Counts of Leucocytes and Serum Anti-oxidative Status in Early-weaned Piglets

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【作者】 孔祥峰刘合军尹富贵印遇龙李铁军黄瑞林

【Author】 KONG Xiang-feng1,2,LIU He-jun2,YIN Fu-gui2,YIN Yu-long1,2*,LI Tie-jun2,HUANG Rui-lin21Department of Food Science and Engineering,Nanchang University,Nanchang 330047,China;2Institute of Subtropical Agriculture,the Chinese Academy of Sciences,Changsha 410125,China

【机构】 南昌大学食品工程系中国科学院亚热带农业生态研究所中国科学院亚热带农业生态研究所 南昌330047长沙410125南昌330047

【摘要】 为了研制高效、安全、无污染的抗生素替代物作为断奶仔猪饲料添加剂,本研究观察了中药超微粉对21日龄断奶仔猪外周血白细胞分类和血清抗氧化功能的影响。结果表明,D7时,超微粉组MDA含量显著小于抗生素组和对照组(P<0.05),NO含量显著小于对照组(P<0.05);D14时,超微粉组NO含量显著大于抗生素组和对照组(P<0.05);D28时,超微粉组NEU计数和百分率及MON百分率均显著小于、LYM百分率显著大于对照组(P<0.05),N/L小于抗生素组(P>0.05)、显著小于对照组(P<0.05),SOD活性显著大于抗生素组和对照组(P<0.05),GSH活性显著大于对照组(P<0.05)。上述指标的变化,与该超微粉对断奶仔猪的防病促生长作用有一定联系。

【Abstract】 The experiment was conducted to determine the effects of Chinese herbal ultra-fine powder with average granule diameter of 30 μm as dietary additive on blood total and differential counts of leucocytes and serum anti-oxidative status in piglets weaned at 21 day old in order to study and develop a novel antibiotic candidate with strong efficacy and perfect safety.The data showed that the ultra-fine powder decreased the content of MDA compared with the other two groups(P<0.05),and of NO compared with that of the supplement-free group(P<0.05) on day 7 after the initiation of supplement.On day 14,the content of NO in the power group was higher than that of the other two groups(P<0.05).On day 28,the powder decreased the numbers of NEU and ratio of NEU and MON(P<0.05),and increased the ratio of LYM compared with the supplement-free groups(P<0.05);the power decreased the N-L ratio compared with the supplement-free(P>0.05) and colistin groups(P<0.05) and increased the activity of SOD compared with the other two groups(P<0.05) and of GSH compared with the supplement-free group(P<0.05).These results suggested that the regulation actions of the Chinese herbal ultra-fine powder to the above-mentioned parameters might be contributed to its functions of preventing disease and promoting growth to the early-weaned piglets.

【基金】 中国科学院知识创新工程重要方向项目(KSCXZ-SW-323);国家973项目(2004CB117502);国家自然科学基金项目(30671517,30528006)
  • 【文献出处】 天然产物研究与开发 ,Natural Product Research and Development , 编辑部邮箱 ,2007年01期
  • 【分类号】S828
  • 【被引频次】14
  • 【下载频次】218
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