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头颈部病变CT灌注成像的初步研究

Initial research of CT perfusion imaging for head and neck lesions

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【作者】 张新捧; 叶兆祥; 肖建宇;

【Author】 ZHANG Xin-peng, YE Zhao-xiang, XIAO Jian-yu(Department of Radiology , Cancer Hospital, Tianjin Medical University, Tianjin 300060, China)

【机构】 天津医科大学肿瘤医院放射科; 天津医科大学肿瘤医院放射科 天津300060; 天津300060;

【摘要】 目的:探讨CT灌注成像技术对头颈部良恶性病变的鉴别诊断价值。方法:对头颈部恶性肿瘤组33例、良性病变组17例行CT灌注成像扫描,盲法分析两组病例的时间密度曲线(TDC)和灌注参数的特点及差异。结果:良恶性病变组间的TDC形态不同,恶性肿瘤组的血容量(BV)、血流量(BF)和表面通透性(PS)值高于良性病变组,平均通过时间(MTT)值短于良性病变组,其差异均存在统计学意义(P<0.05)。结论:头颈部良恶性病变的CT灌注特点不同,CT灌注成像技术对头颈部良恶性病变的鉴别诊断有重要的应用价值。

【Abstract】 Objective: To explore the value of CT perfusion (CTP) imaging in differential diagnosis of benign and malignant lesions in head and neck. Methods: CTP was performed in 50 objectives: 33 in malignant tumor group, 17 in benign lesion group, the time-density curve(TDC)and the data of perfusion parameters were recorded and analyzed statistically. Results: The TDC feature between the two groups had difference. The average of blood volume(BV),blood flow (BF) and permeability surface ( PS) of the malignant tumors were higher than those of benign lesions, the average of mean transit time (MTT) was lower than that of benign lesions ,and they had statistical differences (P<0.05). Conclusion: The features of the CTP are different in benign and malignant lesions in head and neck, CTP is helpful for the differential diagnosis of them.

  • 【文献出处】 天津医科大学学报 ,Journal of Tianjin Medical University , 编辑部邮箱 ,2007年02期
  • 【分类号】R816
  • 【被引频次】2
  • 【下载频次】71
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