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卡泊芬净治疗55例恶性血液病患者侵袭性真菌感染的安全性研究
Clinical study of caspofungin on treatment of 55 malignant hemopathic patients with invasive fungal infections.
【摘要】 目的:评价卡泊芬净治疗血液病患者侵袭性真菌感染的疗效及安全性。方法:采用回顾性分析法统计本院2005年8月—2006年9月住院患者使用卡泊芬净的疗效和不良事件。结果:55例病历分析中显示卡泊芬净总有效率为57.1%,药物相关的不良反应发生率低且较轻。结论:卡泊芬净抗菌谱广,疗效确切,安全性好,是血液病患者抗真菌经验治疗的较为理想药物。
【Abstract】 OBJECTIVE To assess the efficacy and safety of caspofungin for the treatment of invasive fungal infections in hematopathic patients.METHODS Efficacy and Adverse reaction in fifty patients were collected from August 2005 to September 2006,and a retrospective study was preformed.RERULTS The overall efficacy of caspofungin is 57.1% in 55 patients,and the incidence of ADR related to the drug is low and not serious.CONCLUSION Caspofungin is an ideal drug for experiential anti-fungi therapy of hematopathic patients,due to its broad spectrum,good efficacy and excellent safety.
【Key words】 caspofungin; malignant hematology; invasive fungal infections;
- 【文献出处】 天津药学 ,Tianjin Pharmacy , 编辑部邮箱 ,2007年03期
- 【分类号】R733;R519
- 【被引频次】4
- 【下载频次】132