【摘要】 伴侣因子属于热休克蛋白家族中的一员,具有高度的种属保守性及重要的生理功能,能够协助多肽进行正常折叠、组装、转运、降解,并在细胞骨架功能、细胞内的信号转导等广泛的领域都发挥着重要的生理作用,其功能异常会导致多种相关的疾病。本文就其结构和功能及与临床疾病的关系综述如下。更多还原

【Abstract】 Chaperonins belong to hot shock proteins, with highly species conservatism and some important biologic function.They help other polypeptide for their folding,parking,translocating,degradation,and also have other important functions,such as cystoskeleton,intrastital signal transduction.There are some diseases connect with their disfunction.The article is a review about their construction,function and their relations to clinical diseases.更多还原