【摘要】 目的:量化评价治疗剂量153Sm-EDTMP骨显像的效果并探讨其显像条件和临床应用范围。方法:肿瘤骨转移患者52例,99Tcm-MDP骨显像后3d～12d内首次接受153Sm-EDTMP内放射治疗并行153Sm-EDTMP骨显像,将两种骨显像效果进行目测比较,以感兴趣区(ROI)技术分别测得两种显像的M/N比值并将其对数值进行配对资料t检验的统计学处理。结果:治疗剂量153Sm-EDTMP骨显像M/N比值为2.63,高于99Tcm-MDP骨显像M/N比值2.16。治疗剂量153Sm-EDTMP骨显像效果优于99Tcm-MDP。结论:在153Sm-EDTMP治疗骨转移瘤时注射后可直接进行显像观察骨转移病情变化,节省部分骨显像剂99Tcm-MDP的使用。更多还原

【Abstract】 Objective To evaluate the effect of therapeutic dose 153 Sm-EDTMP in skeleton imaging,to discuss condition of imaging and the range of use.Methods 52 patients with bone metastases treated with 153 Sm-EDTMP for the first time.153 Sm-EDTMP skeleton imaging was taked and compared with 99 Tcm-MDP skeleton imaging.The technique of ROI was used and M/N ratio was taked.The data was analyzed in statistical way.Results The M/N ratio of 153 Sm-EDTMP skeleton imaging higher than 99 Tcm-MDP skeleton imaging.The effect of 153 Sm-EDTMP skeleton imaging is higher than 99 Tcm-MDP skeleton imaging.Conclusion 153 Sm-EDTMP can be used as imaging agent at the same time,and 99 Tcm-MDP can be saved.更多还原