【摘要】 目的探讨肝源性溃疡(HU)更合理的治疗。方法通过电子胃镜确诊52例HU,在常规保肝治疗的基础上,随机分为2组。常规组采用奥美拉唑40 mg/d和硫糖铝4 g/d治疗;治疗组在常规治疗组合基础上加用心得安30~60 mg/d治疗,疗程4周,同时比较肝功能不同分级级别的溃疡愈合情况。结果常规组总有效率为60%,治疗组为92.3%(P<0.05),肝功能Ch ild分级A、B两级溃疡显效无统计学意义(P>0.05)但两者与C级相比溃疡显效率有统计学意义(P<0.05)。结论常规治疗溃疡基础上加用心得安可提高溃疡治疗的显效率,且肝功能分级级别增高,溃疡治疗显效率较差。更多还原

【Abstract】 Objective To explore the more reasonable treatment of hepatogenic ulcer(HU).Methods 52 cases with HU diagnosed by electronic gastroscope were randomly divided into two groups on the basis of routine protective liver treatment: routine group and treating group.The routine group was treated with Omeprazole 40mg/d and ulcerlmin 4 g/d,while the treating group with added Propranolol 30~60mg/d.The period of treatment was 4 weeks.The healing of ulcer with different Child grade of liver function was compared.Results The total efficiency was 60% for the routine group and 92.3% for the treatment group(P<(0.05)).The difference of healing of ulcer between the liver function of Child grade A and B was not significant(P> 0.05),but was significant compared with grade C the difference(P<0.05).Conclusions The curative effect can be significantly improved by adding Propranolol to routine therapy.The curative effect of ulcer will decrease with the increasing by Child grade.更多还原