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婴幼儿血管瘤的阶段性治疗

Phase Therapy for Infantile Hemangiomas

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【作者】 曹东升盛辉张林丁浩王邦河汪春兰杨涌

【Author】 CAO Dong-sheng,SHENG Hui,ZHANG Lin,DING Hao,WANG Bang-he,WANG Chun-lan,YANG Yong (Department of Plastic Surgery,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China)

【机构】 安徽医科大学第一附属医院整形外科安徽医科大学第一附属医院整形外科 合肥230022合肥230022

【摘要】 目的探讨糖皮质激素及手术治疗对婴幼儿血管瘤的效果。方法2003年7月~2006年7月对本院收治1~3个月婴儿草莓状血管瘤26例予盐酸曲安奈德注射液瘤体内注射(1 mg/cm2,总量不超过2 mg/kg),2~3周1次,共3~5次;3个月以上婴儿草莓状及海绵状血管瘤50例予手术切除,缺损较大者以皮片移植或局部皮瓣转移修复。其中创口直接缝合38例,植皮3例,以局部皮瓣转移修复9例。结果草莓状血管瘤26例经激素注射1、2次充血减轻,4、5次瘤体均变平,边缘萎缩。手术50例,术后皮片皮瓣均成活,形态良好。结论激素注射是控制小龄婴儿血管瘤安全、可靠、简便方法,对大龄患儿可耐受手术及麻醉则以手术切除效果为佳。

【Abstract】 Objective To evaluate the effect of intralesional corticosteroid therapy and surgical excision for infantile hemangiomas.Methods From Jul.2003 to Jul.2006 intralesional triamcinolone acetonid injections(the does of injection was 1 mg/cm2 per time,but not exceeding 2 mg/kg)were perfomed in 26 infants with hemangiomas aged 1 to 3 months at the first injection.Three to 4 injections were given,spaced 2 to 3 weeks apart.Fifty infants with hemangiomas aged 3 to 16 months were surgical excision.And 38 cases of wound surface were repaired by suture,3 cases by dermatoplasty,and 9 caaes by transferring of skin flap.Results Twenty-six hemangiomas were hyperemia to lessen after 1 or 2 injections,and were softening after 4 or 5 injections.Fifty infants with hemangiomas were surgical excision.Conclusion To the younger infants,intralesional corticosteroid is a simple safe and effective method,but to the older infant who can tolerance operation and anesthesia,surgical excision maybe a proper treatment.

【关键词】 血管瘤糖皮质激素类外科手术
【Key words】 hemangiomaglucocorticoidssurgical procedures
【基金】 安徽省教育厅自然科学基金项目资助(2002Kj149)
  • 【文献出处】 实用儿科临床杂志 ,Journal of Applied Clinical Pediatrics , 编辑部邮箱 ,2007年11期
  • 【分类号】R726.5
  • 【被引频次】8
  • 【下载频次】182
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