【摘要】 目的探讨冠心病患者血脂水平以及血脂代谢异常的流行情况。方法将2005年6月至9月来自北京市、上海市等7城市52家医院心内科所有符合冠心病诊断标准的患者连续入选,共收集有效病例3513例,调查其血脂代谢情况。结果研究对象的血脂代谢异常总发生率为79.7%,<50岁组、50~59岁组、60~69岁组和≥70岁组分别为90.6%,86.9%,80.0%和72.5%,趋势检验差异具有显著性意义(χ2=62.359,P<0.001)。随着年龄的增加总胆固醇(TC)异常、低密度脂蛋白(LDL-C)异常、高密度脂蛋白(HDL-C)异常以及三酰甘油(TG)异常的发生率降低;总的血脂代谢异常发生率亦呈现同样趋势。结论冠心病患者血脂代谢异常发生率较高,尤其是50岁以下患者,应该尽早预防高血脂,从而改善冠心病患者的预后甚至防止冠心病的发生。更多还原

【Abstract】 Objective To investigate the lipidemia of patients with coronary artery disease(CAD)in China.Methods The survey engaged 52 centers in 7 cities in China recruiting patients with coronary artery disease in a hospital-based setting.Each center was asked to recruit all hospitalized patients with CHD from 1-Jun-2005 to 31-Sep-2005.The study population consisted of 3513 patients with CAD.Results Of the 3513 patients,the prevalence of the lipidemia was 79.7%.And the prevalence of the lipidemia in <50,50 to 59,60 to 69,≥70 years group was 90.6%,86.9%,80.0% and 72.5%,respectively.Trend test found that there was significant difference among them(χ2=62.359,P<0.001).There was a clear age-related decrease in the prevalence of lipidemia in the CAD patients.Conclusion Our results demonstrate a high prevalence of the lipidemia in patients with coronary heart disease,especially in <50 years group.Screening for the lipidemia in young patients may prevent progressive CAD.更多还原