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牙周感染与2型糖尿病患者血清白细胞介素-6水平的关系

The effect of periodontal infection on circulating IL-6 in type 2 diabetes patients

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【作者】 谷宇新; 张金廷; 李庆星; 由彦玲; 刘广顺; 李亚威; 王大维;

【Author】 Gu Yuxin, Zhang Jinting, Li Qingxing, et al.Department of Stomatology and Clinical Laboratory, The First Hospital of Hebei Medical University.Shijiazhuang 050031,China

【机构】 石家庄河北医科大学第一医院口腔科; 石家庄河北医科大学第一医院检验科; 石家庄河北医科大学第一医院口腔科 050031; 050031;

【摘要】 目的:探讨牙周感染对2型糖尿病患者血清白细胞介素-6(interleukin-6,IL-6)水平的影响。方法:选择伴重度慢性牙周炎的2型糖尿病患者32例,以年龄(±3)、性别、体重指数(body mass index,BMI)(±1)配比单纯糖尿病对照32例。用酶联免疫测定血清IL-6水平。结果:伴重度慢性牙周炎的2型糖尿病患者血清IL-6测定的阳性百分率明显高于不伴牙周炎的糖尿病患者(P=0.017)。结论:牙周感染可能升高2型糖尿病患者血清IL-6水平。

【Abstract】 Objective: To investigate the effect of periodontal infection on circulating interleukin-6(IL-6) in type 2 diabetes patients.Methods: 32 diabetes patients with advanced periodontitis were participated.They were compared to a group of 32 diabetes patients without periodontal disease, who were matched with regard to age(±3), gender, and body mass index(±1).The serum concentration of IL-6 was measured by ELISA.Result:Differences were statistically significant between the two groups for serum IL-6 by Chi-square test (46.88% vs 18.75%,P<0.05). Conclusions: Periodontal infection may result in higher serum IL-6 in type 2 diabetes patients.

【基金】 河北省自然基金(编号:301379);河北省卫生厅课题(编号:06163)
  • 【文献出处】 实用口腔医学杂志 ,Journal of Practical Stomatology , 编辑部邮箱 ,2007年02期
  • 【分类号】R781.4;R587.1
  • 【被引频次】5
  • 【下载频次】159
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