【摘要】 应用灰色关联度分析法对影响对叔丁基苯硼酸(4-tert-Butylphenylboronic acid)产率的因素进行了关联度分析。分析结果表明:影响对叔丁基苯硼酸产率的因素的影响程度大小顺序为:反应温度>反应时间>反应物的物质的量比,从而确定优化合成条件:亲核取代温度-20℃,n(硼酸三甲酯)∶n(对溴叔丁基苯)=1.4∶1,反应时间为160 min。更多还原

【Abstract】 The influencing factors of 4-tert-Butylphenylboronic acid preparation were analyzed with the Grey Correlation Degree method.The analysis showed that the order of influencing factors as follows : temperature>reaction time>reactants molar ratio.A optimized process for preparation was thus obtained as follows: the reactants molar ratio of the trimethyl borate to 1-bromo-4-tert-butylbenzene is 1.4∶1,the temperature is at-20 ℃,and the reaction time 160 min.更多还原