【摘要】 目的:探讨乳腺原发性恶性淋巴瘤的临床病理特点。方法:对1998年以来收治的5例乳腺原发性恶性淋巴瘤患者的临床表现、治疗方法、病理学特点进行回顾性分析。结果:5例均为女性,平均年龄42.5岁,表现为乳房无痛性肿块、界限清楚、质地中等、表面光滑、与皮肤或胸肌无粘连;针吸细胞学及术前冰冻病理学检查常不能明确诊断,5例手术标本经病理切片检查,光镜下均确诊为乳腺恶性淋巴瘤。结论:本病易误诊,病理学提示本病来源于乳腺黏膜相关淋巴组织,病理切片常发现淋巴上皮损害,免疫组化检查可确定诊断,经手术+化疗和(或)放疗取得较好疗效。更多还原

【Abstract】 Objective:To investigate the clinicopathologic characteristics of the breast primary malignant lymphoma(BPML).Methods:The clinical manifestations,treatment,pathology of 5 patients with BPML have been retrospectively studied.Results:All of the five cases were female,and the average age was 42.5.The presenting complaint was usually a painless mass which was smooth,clear boundary,and did not infiltrate the skin and chest wall.Fine-needle aspiration cytology can not give a clear diagnosis.Operative specimens of 5 cases can diagnose BPML pathologically by light microscope.Conclusion:This disease is easy misdignozed.The pathology indicates that BPML originates from mucosa-associated lymphoid tissue.The lymphoepithelial lesions are often found pathologically.Immunohistochemical can make a clear diagnosis.Surgical operation combined with chemotherapy have a good curative effect.更多还原