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99Tc-亚甲基二膦酸盐注射液治疗乳腺癌骨质疏松及骨痛的评价

The therapeutic effect of 99Tc-MDP for the treatment of osteoporosis and bone pain in patients with breast cancer

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【作者】 刘枫刘淑华任志刚刘致俊

【Author】 LIU Feng,LIU Shu-hua,REN Zhi-gang,LIU Zhi-jun.Guangzhou Tumor Hospital,Guangdong 510095,China

【机构】 广州市肿瘤医院广州市肿瘤医院 510095510095

【摘要】 目的探讨99Tc-亚甲基二膦酸盐注射(99Tc-MDP,云克)治疗乳腺癌激素治疗后骨质疏松及骨痛的临床效果。方法乳腺癌激素治疗后,应用骨密度测定及骨显像检查确诊为骨质疏松、骨痛患者30例。以临床表现及骨痛分为3组,使用99Tc-MDP治疗,同时加用钙剂和活性维生素D3,观察患者的症状、体征。结果经过99Tc-MDP治疗后总有效率为90%,显著率为47%,有效率为43%,无效率为10%。结论99Tc-MDP能有效改善乳腺癌激素治疗后的骨质疏松及骨痛的临床症状,治疗后不良反应少。

【Abstract】 ObjectiveTo explore the effect of 99Technetium Methylenediphosphonate Injection(Yun Ke,99Tc-MDP) on breast cancer patients with osteoporosis and bone pain after the therapy of hormone.MethodsAfter the therapy of hormone,30 patients who were diagnosed were divided into 3 groups according to the clinical feature and bone pain,then treated with 99Tc-MDP,calcium medicament and dihydroxyvitamin D3.Eventually the symptoms and signs of patients were observed.ResultsAfter the treatment of 99Tc-MDP,total efficiency was 90%,excellent efficiency was 47%,efficiency was 43%,inefficiency was 10%.Conclusion99Tc-MDP can effectivelly relieve the clinical symptoms of breast cancer patients with osteoporosis and bone pain after treated with hormone and its side effects are mild.

【关键词】 骨质疏松乳腺肿瘤治疗效果骨痛
【Key words】 OsteoporosisBreast neoplasmsTreatment outcomeBone pain
  • 【文献出处】 山西医药杂志 ,Shanxi Medical Journal , 编辑部邮箱 ,2007年05期
  • 【分类号】R737.9;R580
  • 【被引频次】2
  • 【下载频次】97
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