【摘要】 目的:观察心肺复苏(CPR)后使用生脉注射液对CPR患者脑损伤的影响。方法:选择心肺复苏成功患者51例,随机分为生脉组(28例)和复苏组(23例)。两组患者均给予常规复苏药物治疗,生脉组同时联用生脉注射液。两组均在恢复自主循环后1 h及1 d、3 d和7 d观察脑氧代谢指标(SjvO2、ERO2和Ca-jvO2)的变化,并与15例健康志愿者(对照组)作比较。结果:与复苏组比较,生脉组恢复自主循环后3 d和7 d SjvO2、ERO2和Ca-jvO2均有所改善(P<0.05)。结论:生脉注射液能减轻CPR患者的脑损伤,有利于CPR患者的脑复苏。更多还原

【Abstract】 Objective:To investige protective effect of Shengmai injection on brain damage in patients with cardiopulmonary resuscitation（CPR）.Methods:Fifty-one patients with successful CPR were randomly divided into Shengmai treatment group（n=28）and CPR group（n=23）.Two groups were treated with routine medicine for resuscitation.In addition,the patients in the Shengmai treatment group were treated with Shengmai injection.Cerebral Oxygen Metabolism（SjvO₂,ERO₂,Ca-jvO₂）were recorded at 1 h,1 d,3 d and 7 d after CPR.The results of two groups were compared with 15 health controls（control group）.Results:Compared with CPR group,the cerebral oxygen metabolism（SjvO₂,ERO₂,Ca-jvO₂）were improved in shengmai treatment group（P<0.05）.Conclusion:Shengmai injection can attenuate brain of ischemia refusioninjury after CPR.It is clinically valuable for cerebral resuscitation.更多还原