【摘要】 应用计算机化大鼠心电信号采集和处理系统,引导妊娠第21dSD大鼠和胚胎宫内心电,记录母胎鼠心动周期信号混沌图形参数和数值参数,探讨正常妊娠大鼠母胎心脏系统混沌特征,分析母胎鼠自主神经系统发育的差异性。结果显示,(1)正常胎鼠与孕鼠比较,频率和电压较低,差异均有显著性(P<0.01);(2)正常胎鼠和孕鼠心动周期信号功率谱具有类似于人的心动周期信号功率谱三峰特征;正常胎鼠和孕鼠比较,第二峰、第三峰明显较低;(3)正常胎鼠与孕鼠比较,相对分散度、李雅普诺夫指数和分维数均显著较低,差异均有显著性(P<0.01)。本研究表明,正常胎鼠心动周期信号变化的复杂性低于孕鼠,胎鼠心脏混沌程度低于孕鼠,胎鼠自主神经系统发育尚不成熟。更多还原

【Abstract】 This investigation was made to explore the chaotic characteristics of cardiac system and differences of autonomic nervous system development of normal pregnant rats and fetuses. The electrocardiograms, chaotic graphics and digital characteristics of heart period signal(HPS) of normal pregnant rats and fetuses by day 21st were evaluated with a computerized HPS extracting and analyzing system. Results:①The mean values of frequency and voltage of fetal rats electrocardiograms were lower than those of pregnant rats significantly(P<0.01). ②Being similar to those in human, the chaotic graphics showed three-amplitudes spectral features in both normal pregnant rats and fetuses. However, the second amplitude and third amplitude were lower in fetal rats than in pregnant rats.③The Heart Relative Dispersion, Lyapunov Exponent and Fractional Dimension were significantly lower in fetal rats than in pregnant rats(P<0.01). These findings demonstrated that the autonomic nervous system development of fetal rat was still immature and it exhibited lower complexity of HPS and chaotic degree than that of pregnant rat did.更多还原